S103 Anti-Pseudomonal Bacteriophage Cocktail Reduces Inflammatory Responses in the Murine Lung

Bacteriophage cocktail significantly reduces Escherichia coli O157

Foods contaminated with Escherichia coli O157:H7 cause more than 63,000 foodborne illnesses in the United States every year, resulting in a significant economic impact on medical costs and product liabilities. Efforts to reduce contamination with E. coli O157:H7 have largely focused on washing, application of various antibacterial chemicals, and gamma-irradiation, each of which has practical an...

Anti-inflammatory effect of pristimerin on TNFα-induced inflammatory responses in murine macrophages

Purpose: To investigate the anti-inflammatory effect of pristimerin using RAW 264.7 macrophage cells. Methods: The effect of pristimerin on the RAW 264.7 cells proliferation was determined by CCK8 test. The expression of cyclin D1 and cyclin E1 in RAW 264.7 cells treated with TNF-α and pristimerin was measured by qRT-PCR. The regulation of cytokine IL-1β, IL-6, IL-8, and PGE2 in RAW 264.7 cells...

Balancing anti-inflammatory and anti-oxidant responses in murine bone marrow derived macrophages

RATIONALE The underlying pathophysiology of bronchopulmonary dysplasia includes a macrophage-mediated host response orchestrated by anti-inflammatory peroxisome proliferator-activated receptor gamma (PPARγ) and anti-oxidant nuclear factor (erythroid-derived 2)-like 2 (Nrf2). These have not yet been studied in combination. This study tested the hypothesis that combined inflammatory and oxidative...

Bacteriophage cocktail reduces Salmonella enterica serovar Enteritidis counts in raw and smoked salmon tissues.

The use of bacteriophages for the biocontrol of food-borne pathogens is increasingly gaining acceptance. In this study, the effectiveness of bacteriophages to reduce Salmonella Enteritidis counts was evaluated in raw and smoked salmon tissues. Groups of 25 samples each were contaminated with S. Enteritidis, treated with a phage mix and then incubated for ten days at 18 °C and 4 °C. A significan...

Anti-Inflammatory Role of the Murine